Publications

Papers, preprints, and academic work

See academic CV for a list of publications

Dissertation

PhD Dissertation • In Progress

Hybrid System Dynamics-Agent Based Model for Health-Related Quality of Life in Adolescent and Young Adult (AYA) Cancer Patients and Survivors

Joseph Blochberger (advised by Takeru Igusa, PhD)

Johns Hopkins University, Department of Civil & Systems Engineering

A methodological three-layer computational framework coupling system dynamics, agent-based modeling, and an evolving social network to model HRQoL dynamics in AYA cancer patients. The novel research contribution is the formally specified, verified, bidirectionally coupled architecture of six switchable interfaces with applications to AYA cancer research.

Preprint & Whitepaper

Preprint Manuscript • July 2026

A Tri-Layer Hybrid Simulation of Health-Related Quality of Life in Adolescent and Young Adult Cancer Patients: Verified Architecture, Pattern-Oriented Results, and a Pre-Registered External-Validation Data Request

Joseph Blochberger

Johns Hopkins University (preprint)

Data Request Whitepaper • July 2026

EORTC AYA QLQ-C30 Data Request: External Validation of a Tri-Layer Hybrid HRQoL Model

Joseph Blochberger

Prepared for the European Organisation for Research and Treatment of Cancer (EORTC)

In Preparation

Journal Article • Planned

A Tri-Layer Hybrid Architecture and Simulation of AYA Cancer Health-Related Quality of Life

Joseph Blochberger, Takeru Igusa

Internal draft; venue to be selected

Journal Article • Planned

Network Effects on Health-Related Quality of Life in AYA Cancer Patients Using a Tri-Layer Hybrid Modeling Approach

Joseph Blochberger, Takeru Igusa

Target: IEEE Engineering in Medicine and Biology Society (EMBC) or System Dynamics Society Conference